High-dose interferon generally does not lower blood pressure, it is recommended to choose the appropriate dose of interferon under the guidance of a doctor according to the symptoms of the treatment, blood pressure abnormally lowered is recommended to consult a doctor in time. High-dose interferon is generally used to treat hepatitis B. Hepatitis B is a common infectious disease following infection with the hepatitis B virus. Hepatitis B is usually treated with antiviral, immunomodulators, and gene therapy. Interferon is a common antiviral treatment for hepatitis B. Interferon reduces the amount of hepatitis B virus in the body by inhibiting the replication of the virus, and the mechanism by which interferon works does not result in a decrease in blood pressure. The mechanism of action of interferon does not cause a decrease in blood pressure. Conditions such as weakness, structural abnormalities of the heart, and anemia generally cause a decrease in blood pressure. Large doses of interferon generally do not lower blood pressure, and it is recommended to consult a doctor when blood pressure decreases abnormally.