There is no such thing as the best medication for chapped skin, and the appropriate treatment should be chosen based on the cause of the condition. Cracked skin can be caused by chronic eczema, tinea versicolor or dry skin, which can be treated by applying medicines (such as zinc oxide ointment, clotrimazole ointment, urea ointment) under the guidance of a doctor to clarify the cause of the disease. 1. Chronic eczema: chronic eczema is usually due to the transformation of acute eczema, patients can use zinc oxide ointment, clobetasol propionate cream and so on to carry on the treatment. 2. Tinea versicolor: Tinea versicolor is caused by fungal infections, which can occur in the hands and feet cracking, flaking phenomenon. Patients can use topical antifungal creams, such as clotrimazole cream, terbinafine hydrochloride cream, naftifine ketoconazole cream and so on. 3. Dry skin: when the skin lacks moisture, excessive dryness, there will be cracked skin phenomenon, usually seen in winter. At this time, you can use urea ointment, recombinant human epidermal growth factor gel, polysulfonic acid mucopolysaccharide cream to improve. There are other reasons for patients to have cracked skin, it is recommended to go to the hospital in time for examination, after clarifying the cause of the disease, standardized treatment under the guidance of the doctor. The use of the above drugs need to follow the doctor’s instructions, usually also need to do a good job of skin moisturizing.