Reply from Lu Shuihua, Department of Respiratory Tuberculosis, Shanghai Public Health Clinical Center: Thank you for coming to this area after your visit, where you can communicate online. You can leave a message here if you have any questions. Patient Question: Hello, Dr. Lu. We have been seeing you for six months for a young boy, Cui XX, who was diagnosed with tuberculosis infection and has been seeing you for the last two weeks and all indicators are fine. It’s just that these days, he mentioned that his knee hurts a little when he goes up the stairs. He said he had it before, but he didn’t tell us much about it. We would like to ask, is this related to the medication? Do I need to do anything? Thank you! Response from Lu Shuihua, Department of Respiratory Tuberculosis, Shanghai Public Health Clinical Center: Joint pain, headache, brain fever, appetite, weight gain or loss, and other details may not be important to many parents, or they may feel that they are not related to the disease, so they are often ignored or downplayed, and only tell the doctor after repeated questioning. Tell me about these details. In clinical practice, I often find that patients or family members are very eager to bring a large list of labs for me to analyze but forget or neglect to describe their symptoms and changes in their condition, which is not right.