The hazards of long-term use of diuretics, including the emergence of water, electrolyte disorders, allergic reactions, affecting renal function, etc., are as follows: 1, water, electrolyte disorders: through the action of the drug, it can affect the electrolytes, water reabsorption of filtrates in the kidneys. Because most diuretics, have the role of potassium and sodium excretion, long-term large amounts of drugs, while not properly monitoring and adjusting the drug, can make the body lose too much potassium and sodium ions, resulting in hypokalemia and hyponatremia, which in turn cause related symptoms. For example, systemic symptoms such as fatigue, drowsiness and nausea. At the same time, it may cause a large amount of water loss, dehydration and other related symptoms; 2, allergic reactions: such as causing rashes and other allergy-like reactions; 3, affecting renal function: some diuretics have a certain effect on renal function, and after long-term large amounts of drugs, it may affect the renal function, resulting in renal insufficiency. Therefore, diuretics must be used under the guidance of a doctor, while regular monitoring is required.