Pain in both hands can be caused by several reasons: first, peripheral neuritis, peripheral neuritis is often symmetrical onset in both hands, can have glove, glove-like changes, often accompanied by diabetes, then early examination to diagnose, early nerve nutrition and physical therapy. Second, multiple osteoarthritis, when the elderly have multiple osteoarthritis, there can be pain in two finger joints, it is necessary to take an X-ray of the hand to diagnose. Third, rheumatism and rheumatoid rheumatism, rheumatism and rheumatoid rheumatism can involve multiple joints of the fingers, often symmetrical onset, there can be morning stiffness, severe cases will have finger deformities, then early blood tests and x-ray of the hand to diagnose and treat. Fourth, ankylosing spondylitis, ankylosing spondylitis can involve the fingers of both hands in severe cases and lead to pain in the finger joints, which can be accompanied by pain in the sacroiliac joints and morning stiffness, which requires blood tests and X-rays of the sacroiliac joints and lumbar spine for diagnosis and treatment.