Bubonic plague is a virulent infectious disease mainly transmitted by the plague bacillus through rat fleas, and has long been classified as a Grade A infectious disease by the state, which is very serious. Plague is generally first popular among rats, and once the epidemic spreads among rats, it becomes a direct source of infection for people infected with plague. Plague is highly contagious and has a high mortality rate. The main manifestations are high fever, lymph node swelling and pain, bleeding tendency, special inflammation of the lungs and skin, meninges and other lesions, which can cause sepsis, life-threatening. Daily life must pay attention to prevent the occurrence of plague, first of all, should exterminate rats and fleas. Once found infected with plague patients, should be isolated on the spot, avoid transit. The secretions and excretions should be thoroughly sterilized or directly incinerated. Protective measures should be taken to avoid the spread of plague.