Hot flashes can be treated with medication under the guidance of a doctor, and commonly used medications include Zhi Bai Di Huang Wan and Mai Wei Di Huang Wan. However, the specific medication should be decided by the doctor according to the patient’s condition. Hot flashes on the palms of the hands may be a manifestation of yin deficiency, and may be accompanied by flushing on the cheekbones, irritable heat in the heart (irritability and sultriness), and night sweating (abnormal sweating after going to sleep, but sweating stops after waking up). Commonly used medications include Zhi Bai Di Huang Wan and Mai Wei Di Huang Wan. Zhi Bai Di Huang Wan, composed of Zhi Mu, Huang Bai, Shu Di Huang, Cornu Cervi (made), Mudan Pi, Shan Yao, Poria, Zedo. It is used for hot flashes and night sweating, dry mouth and sore throat, tinnitus and spermatorrhea, and short and red urine (small amount of urine with dark yellow color) caused by yin deficiency and fire exuberance. It is used for hot flashes and night sweating caused by deficiency of lung and kidney yin, dry throat, dizziness and tinnitus, soreness and weakness of waist and knees. Contraindicated for those with external wind-heat, sore throat and internal heat. It is not recommended to take if there is phlegm obstructing the lungs, coughing, excessive phlegm with white sparse, loose stools (thin and unformed feces). If the symptoms of hot flashes in the palms of the hands are not relieved for a long time or accompanied by other discomforts, consult a doctor in time to find out the cause and carry out targeted treatment.