Urinary microalbumin 40mg/L usually does not need treatment if it is caused by physiological factors; however, it may also be caused by pathological factors such as glomerulonephritis, nephrotic syndrome and so on, at which time it can be relieved by medication. Therefore, attention should be paid to find the causes of micro-proteinuria. 1. Physiological factors: it may be caused by lack of sleep, overwork, strenuous exercise and other reasons for the elevation of urinary microalbumin, generally do not need treatment, and can be returned to normal after a good rest. 2. Pathologic factors: (1) Glomerulonephritis: It is a disease in which the glomerular filtration function is impaired due to infections, diseases and other reasons, resulting in hematuria, proteinuria, edema and hypertension as the main manifestations, which will lead to elevated urine microalbumin. Drugs such as cyclophosphamide and cyclosporine can be used. (2) Nephrotic syndrome: with large amount of proteinuria, hypoproteinemia, edema, hyperlipidemia as the basic features. It will lead to elevated urinary microalbumin. Drugs such as prednisone can be used. Urine microalbumin 40mg/L may also be related to prostatitis, urinary stones and other diseases, you should go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment under the guidance of the doctor.