There is always a burning sensation in the stomach mostly due to chronic gastritis, peptic ulcer, stomach tumors and other diseases, which can be treated by adjusting lifestyle and dietary habits, taking omeprazole, bismuth potassium citrate, amoxicillin and other medications, surgery and so on. 1. Adjusting life and diet habits: patients should pay attention to diet, with light, easy to digest, balanced nutrition, avoiding cold, spicy and other stimulating food, greasy and other indigestible food and strong tea and coffee, etc., and quit smoking and drinking to avoid stimulation of gastric mucosa. At the same time, we should pay attention to avoid overeating, try to eat small meals, chewing and swallowing slowly, and avoid staying up late and working hard. 2. Taking drugs: patients with increased gastric acid secretion, gastric mucosal damage, etc., can take omeprazole, ranitidine and other acid inhibitors to inhibit the secretion of gastric acid, take bismuth potassium citrate, magnesium aluminum carbonate and other gastric mucosal protection drugs to reduce the stimulation of the gastric mucosa. If the patient is accompanied by Helicobacter pylori infection, the patient can take amoxicillin, metronidazole, norfloxacin, clarithromycin and other antibiotics at the same time for eradication treatment. 3. Surgery: If the patient is due to gastric polyps, stomach cancer and other diseases, he/she can consider receiving surgical treatment. If the patient has a long-term or repeated burning sensation in the stomach, it is recommended to consult a doctor in time to identify the cause of the disease and carry out targeted treatment. The medication should be taken strictly according to the doctor’s prescription, and should not be used on its own, so as not to delay or even aggravate the condition.