Scabies nodules can not be pierced to prevent secondary infection, and in severe cases may evolve into pustules. The correct treatment measures for scabies nodules include medication, physical therapy, surgery and so on. 1. Medication: patients can follow the doctor’s instructions in the nodules with tacrolimus ointment, which can play an anti-inflammatory role, if the patient has a strong sense of itching, can be operated by the doctor in the nodules local injection of tretinoin hormone solution, which can play a stronger anti-inflammatory effect, thereby relieving the itching sensation. 2. Physical therapy: the more commonly used treatment is carbon dioxide laser therapy, through the high energy laser makes the local cell tissue necrosis, so as to eliminate the nodules. Liquid nitrogen cryotherapy is also available. 3. Surgery: If the results of the above treatment options are not satisfactory, surgery can be chosen to remove the scabies nodules. It is recommended that the patient go to the hospital in time, under the guidance of the doctor to carry out regular treatment. The application of drugs need to strictly follow the doctor’s instructions, if there is any discomfort, you can stop the medication to see a doctor.