Whether or not renal tubular damage can be reversed is related to factors such as the etiology and duration of the damage. If the cause can be corrected quickly and this damage occurs within three months, it may be reversible; if the cause cannot be corrected in time and chronic renal insufficiency develops, it may not be reversible. Renal tubular damage can be seen in the necrosis of renal tubular epithelial cells caused by dehydration. After adequate rehydration, the patient’s renal injury can be recovered and the renal tubular epithelial cells can be regenerated. This renal tubular damage can be reversed. If some causes are more difficult to remove, such as dry syndrome, systemic lupus erythematosus and other immune diseases. There are also some causes that continue to damage the renal tubules for more than three months and develop into chronic renal insufficiency, at which time the renal tubular damage cannot be reversed. If patients find renal tubular damage, it is recommended to go to regular hospitals in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.