Biological clock disorders most commonly lead to sleep disorders, the biological clock is actually the body’s internal routine, when the patient because of certain activities or certain behaviors, resulting in biological clock disorders, the main symptom will lead to the patient’s sleep problems. When sleep disorder occurs, a lot of problems will appear, such as long-term poor sleep, there will be poor concentration and memory loss, the patient’s thinking ability will also decline, in the daytime will be manifested as mental depression, physical fatigue, work and study efficiency will be greatly reduced, and prone to make mistakes. Long-term insomnia patients will also have a loss of appetite, there will be a decline in immunity, more prone to colds or pneumonia and other inflammatory problems. Therefore, patients with biological clock disorders, must be adjusted from their own lifestyle, you can take oral sleeping medication, such as diazepam, eszopiclone to help patients adjust the biological clock.