The main reason for not having menstruation during menopause is that the ovaries do not secrete estrogen and progesterone anymore, and the endometrium will not change cyclically with the hormones secreted by the ovaries, so menstruation will not occur. Due to the decline of ovarian function and the decrease of estrogen level, the uterus will atrophy, the endometrium will become thin, the vaginal mucosa will also become thin, and the vaginal folds will be spread out and flat. Clinically, insomnia, dreamy or panic attacks, and agitation may also occur. All these are the manifestations of menopause, so the lack of menstruation during menopause is mainly related to the rapid decline of hormone levels in the body.