Purple palms may indicate purpura, Raynaud’s syndrome, hypoxia and other diseases. 1. Purpura: It is a kind of subcutaneous hemorrhage caused by the exudation of red blood cells from the blood vessels to the skin, connective tissues or mucous membranes. It is mainly caused by abnormalities in the structure and function of blood vessel walls, abnormalities in the number or function of platelets, and abnormalities in coagulation. It is manifested by the change of epidermal color, which may become purple or brownish red, and the color does not change after pressure is given. 2. Raynaud’s Syndrome: It is a change characterized by episodes of pallor, cyanosis and flushing of the skin of both hands induced by cold or emotional factors. It is mainly caused by episodic spasm of the finger arteries. 3. Hypoxia: purple palms can be seen in hypoxic diseases, such as lobar pneumonia, lung tumors, chronic obstructive pulmonary disease, etc. Lungs are an important organ for gas exchange, when lung disease causes insufficient oxygen inhalation, carbon dioxide retention, the patient will appear palms of the purple, purple lips, dyspnea phenomenon, through the examination of the chest CT examination can be identified. In addition to the above diseases, purple palms can also be seen in other diseases, which require timely hospitalization for differential diagnosis and treatment.