Generalized weakness and diarrhea are mainly considered to be related to acute gastroenteritis, electrolyte disorders, chronic intestinal diseases and other causes. 1. Acute gastroenteritis: abdominal pain, diarrhea, vomiting and other intestinal symptoms will occur during acute gastroenteritis, diarrhea, vomiting will be accompanied by severe weakness, fatigue and so on. 2. Electrolyte disorders: when severe diarrhea occurs, it can lead to electrolyte disorders, which is manifested as generalized weakness. 3. Chronic intestinal diseases: when suffering from digestive tract tumors, ulcerative colitis and other diseases, weakness, diarrhea and other uncomfortable symptoms will also occur. It is recommended to go to the hospital for examination and treatment after the cause of the disease is clarified under the guidance of the doctor.