Both Southern ginseng and Northern ginseng are yin nourishing herbs, and both have certain effects, such as nourishing yin and clearing the lung, benefiting the stomach and generating body fluid. However, Southern ginseng is characterized by its specialization in attacking the lung, favoring to clear the lung and dispel phlegm to stop cough, while Northern ginseng specializes in entering the stomach, favoring to nourish yin and produce fluid to stop thirst. There are many clinical applications of Nan Sha Shen and Bei Sha Shen, both of which can improve the symptoms related to Yin deficiency and are suitable for tonic, especially in combination with ginseng and other drugs. Southern ginseng nourishes the qi of the lung and spleen, which is ideal for patients who suffer from weakness, low food intake and spontaneous sweating; Northern ginseng nourishes the yin of the lung and stomach, which is more suitable for patients who suffer from internal heat, dry cough, low phlegm and even dry mouth after long-term illness.