Peeling on the soles of the feet may be caused by physiological factors such as dry skin, or it may be caused by diseases such as athlete’s foot and herpes sweat, which need to be removed by general treatment and medication. 1. Physiological factors: If the skin on the feet is too dry, it may lead to localized peeling, generally do not need special treatment. It is recommended to pay attention to the cleanliness of the soles of the feet and avoid localized friction or long-term walking. 2. Tinea pedis: the skin on the soles of the feet may be caused by tinea pedis, the patient should change shoes and socks diligently, the patient also needs to follow the doctor’s instructions to apply antifungal drugs, with antibacterial and antiseptic efficacy, such as miconazole, econazole cream and so on. 3. Sweat herpes: sweat herpes belongs to a kind of eczema, blisters dry may also lead to the soles of the feet skin, the patient should avoid excessive cleaning, it is recommended to follow the doctor’s instructions for external glucocorticoid ointment, such as tretinoin, hassinide solution, etc., with anti-inflammatory effect. There are many reasons for the peeling of the soles of the feet, after excluding physiological factors, it is recommended that patients seek medical examination and cooperate with doctors for standardized treatment.