If you need to take antibiotics as well as probiotics, at least two hours after taking the antibiotics, then take the probiotics. In general, it is not recommended to take antibiotics and probiotics at the same time. Because antibiotics will kill the flora in the intestinal tract, and this killing is not distinguished between beneficial or harmful bacteria. Therefore, in some cases, taking both at the same time may aggravate the condition. In addition, antibiotics and probiotics taken at the same time can sometimes cause gastrointestinal dysfunction, leading to abdominal pain or diarrhea and other symptoms, so the two should not be taken at the same time. Patients are advised to seek medical advice on how to take antibiotics and probiotics properly. In addition to the time of taking, probiotics should not be taken with hot water, and should be taken with cool boiled water.