Vitamin B1, also known as thiamine, is mainly used for the prevention and treatment of foot disease and various diseases, such as polyneuritis and various nerve injuries. Vitamin B1 plays an important role in energy metabolism in the body, as vitamin B1 can be used as an inhibitor of cholinesterase and is involved in regulating the metabolism of acetylcholine, so it also plays a role in nerve conduction. Therefore, vitamin B1 deficiency can cause chronic peripheral neuritis and other neuromuscular degenerative lesions, so vitamin B1 is used in the prevention and treatment of foot disease and the adjuvant treatment of various diseases, such as polyneuritis, drug nerve injury, pediatric paralysis, pediatric enuresis, systemic infection, hyperthermia, diabetes, myocarditis, digestive disorders, hyperthyroidism, pregnancy, etc. Oral use of this drug does not increase the amount of absorption when the dose is increased, while large doses of intramuscular injection of vitamin B1 should be careful to prevent allergic reactions.