Whether daily saline nasal rinsing leads to nasal mucosal fragility is related to the concentration of saline and whether it is done accurately. If it is 0.9% saline, it will not lead to nasal mucosal fragility, but incorrectly using hypertonic saline to rinse the nasal cavity may lead to nasal mucosal fragility. The use of saline nasal rinses improves mucosal cilia function and increases cilia clearance; controls nasal inflammatory mediators and reduces nasal mucosal edema; and the rinsing solution has a physical or mechanical removal effect. However, hypertonic saline causes irreversible inhibition of ciliary function when the osmolarity exceeds 5.5%. Cilia stop moving at osmolarity of 4.5 to 5.5%, and although cilia may resume movement when the concentration is restored to 0.9% saline, daily use can lead to nasal mucosal fragility. It is recommended that patients go to the hospital to consult a doctor before starting to wash the nose with saline, and at the same time to carry out correct and scientific operation to avoid causing damage to the nasal mucosa.