The generic name of Nexium is Esomeprazole, and clinical studies have shown that for patients with reflux esophagitis, both drugs are effective without much difference. Esomeprazole and rabeprazole belong to the third generation of proton pump inhibitors, can effectively inhibit gastric acid secretion, protect the gastric mucosa, the common adverse reactions of this kind of drugs include impaired hepatic function, impaired renal function, etc., and is prohibited in patients who are allergic to this kind of drugs. In addition, in addition to the application of proton pump inhibitors, reflux esophagitis needs to be combined with gastrointestinal stimulants and gastric mucosal protectants, otherwise the condition is prone to recurrence. The above drugs should be used under the guidance of specialized physicians. If the patient is diagnosed with reflux esophagitis, it is recommended to use the medication under the guidance of a doctor and avoid self-medication.