Prolonged staying up all night with a pronounced pulse beating at the temples requires a timely visit to the hospital to check blood pressure and heart rhythm. If there are abnormalities, stabilize the blood pressure and heart rhythm. If there is no abnormality in the examination, it is recommended that the patient corrects the routine of work and rest and avoids staying up all night. Staying up late for a long time may lead to disorders in the regulation of nerve function, which may easily lead to the development of hypertension. If high blood pressure occurs, it may be manifested as obvious pulse beating at the temples. At this time, it is necessary to formalize the consultation in the cardiology department, monitor the blood pressure, and be guided by a professional doctor to lower the blood pressure treatment, which can be applied to amlodipine, timosartan and other drugs. Staying up late for a long time may also lead to a rapid heart rate and some arrhythmias, which may be manifested in a pronounced pulse at the temples. This requires a visit to the cardiology department for an electrocardiogram or even a 24-hour ambulatory electrocardiogram to clarify the heart rhythm and, depending on the rhythm, to guide anti-arrhythmic treatment. The drugs are different for different arrhythmias. In the case of premature beats, propafenone, mesylate, etc. can be applied, and in the case of sinus tachycardia, metoprolol, etc. can be applied. If the patient’s blood pressure and heart rhythm are normal, and further examination of the cardiac ultrasound is normal, if necessary, can be consulted in the Department of Neurology, cerebrovascular and other aspects of the examination. It is recommended to avoid staying up late and improve the routine of life.