Painful buttocks and legs need to be treated with a clear cause, and there is no quick fix. Common causes include sciatic nerve compression, lumbar disc herniation, trauma, etc. Conservative treatment, medication and surgery can be used. 1. Sciatic nerve compression: common in sedentary patients, or trauma resulting in sciatic nerve contusion, resulting in buttock pain and leg pain, treatment methods include non-steroidal anti-inflammatory drugs (such as ibuprofen), physical therapy, lidocaine injection, and surgical treatment. 2. Lumbar disc herniation: lumbar disc herniation can also cause lumbago and buttock pain, the treatment includes lumbar protection, local physical therapy, nutritive nerve drugs (methylcobalamin), pain relief (such as celecoxib), dehydration (such as furosemide), hormone therapy (such as prednisone), and surgical treatment. 3. Trauma: low back pain and buttock pain caused by trauma, such as falling from height, if the injury is relatively mild, conservative rest treatment can be carried out, if there is a fracture or serious nerve compression symptoms, early surgical treatment should be carried out to restore bone continuity. Pain in the buttocks and leg pain may also exist for other reasons, it is recommended to consult a doctor in time to identify the causes, give targeted treatment, the above drugs need to be used under the guidance of a doctor.