Persistent eczema belongs to the category of “eczema” in Chinese medicine, which is divided into wind-heat impregnated skin evidence, damp-heat impregnated evidence, spleen deficiency and dampness impregnated evidence, and yin deficiency and blood dryness (deficiency of yin and fluid, and dryness and heat in the blood), etc., and can be treated with elimination of wind dispersal, gentian diarrhea and liver soup, elimination of dampness and gastrointestinal ling soup, and cooling blood and four substance soup, respectively. Wind-heat impregnated skin syndrome: the onset of the disease is rapid, the skin lesions are round or oval light-red patches, with a small amount of furfuraceous scales on the surface; accompanied by heartburn and thirst, urine is slightly yellow; the moss is white or thinly yellow, and the pulse is floating and numberless. The treatment is to remove wind and clear heat to stop itching, and the commonly used prescription is eliminating wind. Dampness-heat immersion syndrome: dampness-heat evil invasion, with redness, swelling, wetness, itching, ulceration and running water on eyelid margins, ears, corners of the mouth and toes, etc. The treatment is to clear heat and dry dampness (removing heat and drying dampness) to stop the itching, and the commonly used prescription is Longdian Diarrhea and Liver Soup. Spleen deficiency and dampness syndrome: slower onset, flushed lesions, itching, erosion and oozing after scratching, visible scales; accompanied by low energy level, fatigue (lack of spirit), abdominal distension and loose stools (loose stools are not shaped). The treatment is to strengthen the spleen and relieve dampness to stop itching, and the common prescription is to remove dampness and stomach ling soup. Yin deficiency and blood dryness syndrome: the patient manifests five heart-heat (heat in the heart of the hands and feet, and self-consciousness of heart and chest heat), zygomatic redness (redness of the cheeks and zygomatic bones), internal disturbances of deficiency heat, night sweating (abnormal sweating after falling asleep, but sweating stops after waking up), and bone vaporization and laborious heat, etc. The treatment is to nourish the yin and nourish the blood (to replenish the blood in the body), moisten the dryness and stop the itching, and the commonly used prescription is Cooling Blood and Four Substances Tang. The adverse reactions or contraindications of the above drugs are still unclear, and should be used under the guidance of a professional Chinese medicine practitioner.