Hydroquinone cream is a skin discoloring agent, mainly used for the treatment of chloasma, freckles and post-inflammatory hyperpigmentation spots and so on. After the use of the drug patients may experience burning sensation, occasionally see local allergic reactions, such as local contact dermatitis, at this time the drug should be stopped immediately and given treatment. For children under 12 years of age and pregnant women should be prohibited from using, each use of the area should not be too large, can not be used for the eyes and wounds around the spot lesions, to avoid sunlight, too much sunlight will occur freckles, can only be used in the lesions of the site, do not apply on the normal skin, the cream should be prohibited from using once the discoloration. Before using the drug should be its sensitivity to skin test, can be applied in the undamaged skin for 24 hours, such as a small amount of erythema does not have to prohibit the use of the drug. However, if itching, blistering or specific inflammatory manifestations occur at the site of application, it is advisable to discontinue the use of the drug.