Red spots on the face with high fever may be caused by toddler emergency rash, rubella, measles and other factors. 1. Childhood emergency rash: mainly caused by human herpesvirus type 6 and 7 infection, mostly seen in children from 1 to 3 years old, after the disease, usually have a fever for 3 to 5 days, followed by the appearance of rosy erythematous papules, papules usually after the appearance of the fever again. 2. Rubella: This is an acute respiratory infection caused by the rubella virus. It usually presents with fever, maculopapular rash, and enlarged lymph nodes behind the ears and occiput. This condition is usually characterized by a low-grade fever, and a small number of patients may have a high fever. 3. Measles: generally caused by measles virus, it is infectious, and in the early stage, there may be high fever, measles mucous membrane spots and severe cold-like symptoms, and then brownish-red maculopapular rash may appear, and after it subsides, it may leave hyperpigmentation and skin desquamation. In addition, there are many infectious or non-infectious dermatologic conditions that may present the same symptoms and should be identified in a timely manner by paying attention to hospital visits. Therefore, if the symptoms of red spots on the face with high fever appear, it is recommended to consult a doctor in time to avoid delaying the condition and causing adverse consequences.