The chronic complications of diabetes can come in all shapes and sizes, but the clinical manifestations are often invisible and colorless. The diabetic foot is relatively obvious, and many friends who have never studied medicine can often point out, “It’s a diabetic rotten foot. Severe diabetic foot can lead to toe amputation, disability and even death. So what are the characteristics of a severe diabetic foot? It can be summarized as inconsistent, that is, several inconsistencies. First, the degree of trauma and internal damage of the diabetic foot is inconsistent. Many of the external damage is not serious or the trauma is small, but the internal damage is very serious. Ben Abel has been diabetic for 20 years and had only a 1cm-sized ulcer on the back of his left foot for 2 weeks. With daily disinfection and other treatments in an outside hospital, the surface trauma gradually shrank, but he became increasingly mentally ill with a low fever, did not want to eat, and showed signs of sepsis. He came to the hospital to examine the foot without obvious redness, swelling, heat and pain, and measured that the circumference of the left foot was wider than that of the right, so he was immediately given dilation and found a large amount of internal pus and necrotic tissue. Angiography of the lower limbs revealed severe stenosis of the blood vessels in the lower leg, and stents were placed. After comprehensive treatment, the condition gradually improved, and the wound healed after 3 months, and the affected foot was preserved. Second, the degree of injury at the onset of diabetic foot ulcers is inconsistent with the consequences. Master Zhang had a slight abrasion on the epidermis of his left foot during labor, but did not pay attention to it and insisted on labor. The wound did not heal for more than 1 month, but instead appeared to expand in extent with suppuration. The examination found that the blood sugar was significantly elevated. He was given glucose reduction, anti-infection and local implantation with poor results. He came to the hospital for examination and found that the foot deformity was bunion, and the radiograph suggested mild infection of the bone cortex and necrosis of the skin graft. He was given debridement, anti-infection, glucose lowering, braking and local physiotherapy, etc. The wound healed slowly and the bone infection disappeared. Third, the dominant cause of diabetic foot is inconsistent. Diabetic foot occurs for a variety of reasons, including vascular occlusion, neuropathy, foot deformity, infection, etc. Shen, who has been diabetic for many years, came to our hospital this time with spontaneous necrosis and suppuration of two toes of her left foot. She had typical foot deformity, neuropathy, infection and gangrene. The routine examination before toe amputation revealed severe occlusion of the arteries in the left lower extremity, which made it impossible to perform surgical options for revascularization such as stent installation, balloon dilation and vascular bypass, and only amputation could be performed from the thigh area. Fourth, the occurrence of diabetic foot is inconsistent with the patient’s age, disease duration, and blood glucose level. Mr. Di, 30 years old, works in catering and is obese and afraid of heat. Due to wearing shoes always stuffy and wet, his left foot began to rot after breaking, gradually expanding in scope and emitting a foul odor. He went to the local clinic and was found to be diabetic, but the elevated blood glucose was not very serious. There was no deformity in the foot, and the vascular condition and nerve condition were also good on examination. The decomposition became more and more severe, and amputation of one toe did not control the disease and was rejected by several hospitals. After being admitted to the hospital, the necrotic tissue was completely removed, and he insisted on twice daily drug changes, as well as comprehensive treatment such as glucose lowering, and his condition was gradually controlled, the wound healed, and he returned to work without further toe amputation. Although the clinical manifestations of diabetic foot are complex and variable, the principles of prevention are the same. Those who do not have diabetes should prevent it by maintaining a good lifestyle and regular medical checkups. Those who already have diabetes should not stress. The first step is to keep blood glucose control up to standard, quit smoking, and control blood pressure and lipids. Wear loose shoes and socks, pay attention to skin cracking in winter and scratches, scratches and insect bites in summer, do regular podiatry screening and treat neuropathy, vascular disease and foot deformity in time. If there is a skin rupture promptly to the regular hospital, can greatly reduce the incidence of diabetic foot ulcer ulceration.