There is no fastest and most effective treatment for roundworms. Usually it is treated with anthelmintic medication, and if there are complications of intestinal obstruction or perforation, surgical treatment is needed, depending on the specific condition. Ascaris lumbricoides is a disease caused by parasites in the small intestine or other organs of the human body. Infection with ascaris lumbricoides may cause fever, general malaise, urticaria and other symptoms, and if there is ascaris lumbricoides obstruction, it may also be life-threatening. Roundworms can be treated with anthelmintics such as mebendazole, ivermectin and albendazole. If serious complications occur with obstruction or perforation, timely surgical treatment is needed to remove the roundworms and repair the damage they have caused. Daily attention should be paid to personal hygiene, washing hands before and after meals, not drinking raw water and not eating unwashed food to avoid roundworm infection. Patients with roundworms are advised to seek timely medical attention and treatment under the guidance of a physician, and to follow the doctor’s instructions for medication, not self-medication.