Patients who have undergone valve replacement are routinely given anticoagulants postoperatively to avoid embolic complications. In particular, lifelong anticoagulation is required after mechanical valve placement. So, will oral anticoagulation in female patients of childbearing age with valve replacement affect pregnancy and childbirth? First of all, patients with replacement bioprosthetic valves generally only need to take oral anticoagulants for 3 to 6 months, so after discontinuing anticoagulants, women of childbearing age can get pregnant and have children normally. However, it is important to take good care of the pregnancy to avoid cardiac insufficiency. Second, patients with mechanical valve replacement require lifelong anticoagulation, so careful consideration should be given when deciding to become pregnant. The reason for this is that coumarin-based anticoagulants (warfarin) taken during the first trimester of pregnancy carry a risk of malformation of the fetus. Therefore, in the first three months of pregnancy, heparin-based drugs (such as heparin or low-molecular heparin) must be switched to anticoagulation; from the fourth month to the 38th week of pregnancy, coumarin-based anticoagulation can be used; from the 38th week of pregnancy, although the fetal organs are relatively mature, heparin-based anticoagulants should be used to prevent premature delivery or other causes of bleeding from the uterus and other birth canals; because the anticoagulation process increases the risk of bleeding during pregnancy and delivery Because of the increased risk of bleeding during anticoagulation, anticoagulants are discontinued 12 hours before the planned delivery; after delivery, the bleeding from the birth canal basically stops and can be replaced with coumarin-based anticoagulation. The prothrombin time and the international standard ratio should be strictly tested while taking coumarin-based anticoagulants. Therefore, it is possible for patients of childbearing age to get pregnant and have children after valve replacement, and they should consult more cardiologists and obstetricians and gynecologists before and after pregnancy, and do a good job of perinatal anticoagulation therapy and pregnancy care.