Whether breast nodules can take the third injection of the new crown vaccine needs to be analyzed in conjunction with the patient’s condition, and the condition is relatively stable can be vaccinated under the guidance of the doctor. Breast nodule is an elevated swelling on the breast, the new crown vaccine is a relatively safe vaccine, after injection, there are few adverse reactions, the adverse reaction is mainly manifested as allergic reaction, fever reaction, etc., and does not affect the breast nodule. Patients with benign breast tumors such as fibroadenomas, malignant tumors and malignant tumors of the breast can receive the third dose of the vaccine if their conditions are stable, they are not undergoing treatment, and they are in good physical condition. Breast malignant tumors such as breast cancer patients who are in the treatment stage, or breast cancer patients who have just had surgery, due to the suppression of the immune system, this situation is not recommended to receive the third shot of the new crown vaccine. In the case of malignant tumors of the breast, early surgical treatment is required and vaccination is not recommended for the time being.