Pantoprazole sodium treats acute upper gastrointestinal bleeding caused by peptic ulcers, reflux esophagitis, Helicobacter pylori infections and ulcers.The mechanism of Pantoprazole in treating the above disorders is to reduce the secretion of gastric acid by inhibiting the H-K-ATPase on the cells of the stomach wall, also known as the H-pump or the proton pump, in order to reduce the stimulation of the ulcerated surfaces by the excessive gastric acid. The main adverse effect of NSAIDs is the irritation of the gastrointestinal tract, which can lead to gastric ulcers and bleeding in severe cases. Elderly patients with gout, rheumatoid arthritis, and osteoarthritis who have been taking NSAIDs for a long time can also use Pantoprazole Sodium to prevent peptic ulcers.