Wake up at 3-4 o’clock and can’t sleep, the reason for the above phenomenon may be the following two cases: First, depression: depression has a characteristic that can’t sleep after waking up, and wake up earlier than normal to wake up more than two hours in advance, which is called early waking up. In addition to early waking, depression has low mood, loss of interest, loss of energy, fatigue, and somatization symptoms, such as headache, dizziness, etc., the duration of the disease more than two weeks. If the above symptoms are consistent, consider depression, need to take antidepressants to treat. Second, physiological conditions: mostly seen in the elderly over 60 years old. If you go to bed earlier at night, such as after 10 o’clock, the elderly sleep 5-6 hours is enough. Some patients often wake up at 4 o’clock, but energetic during the day, does not affect the normal study, life, work, for this situation can not have to intervene.