Oxyrhynchus generally refers to the gallbladder, bile duct or liver duct stones of bovine animals, etc. However, most of the oxyrhynchus on the market is artificial oxyrhynchus, which belongs to a Chinese herb with detoxifying effect and can be used for sore throat and mouth sores, and also has the effect of detoxifying fever and resolving phlegm, etc. It is also widely used in the clinic and has a certain sedative effect on patients with convulsions. However, whether the patient is suitable for taking Niuhuang, but also need to be treated by a professional doctor to identify the evidence, according to the condition and indications for individualized treatment. In the clinical practice, most of the pills are made of Niuhuang, which has therapeutic effects both internally and externally, but it is not suitable to be decocted, as it may reduce the efficacy of Niuhuang and thus affect the therapeutic effect. If you choose to use it externally, you can grind it and apply it to the affected area. However, it is more often used in combination with other Chinese medicines to make some convenient Chinese medicines, such as Niuhuang Detoxification Pill, Angong Niuhuang Pill, Xihuang Pill, Niuhuang Shangqing Pill, Niuhuang Qingxin Pill, etc., which can be taken according to the drug instructions or doctor’s guidance. In addition, Niuhuang is cold in nature and should not be taken in large doses as a single medicine for patients with problems such as wind chill and spleen and stomach deficiency. Also, care should be taken with caution for special populations such as infants, the elderly, pregnant women or those with pre-term abortions. For patients suffering from digestive system diseases that require long-term treatment, such as chronic gastritis and chronic enteritis, long-term use is not recommended. Moreover, Niuhuang has the effect of lowering blood pressure and should be taken with caution by patients with low blood pressure to avoid aggravation of symptoms. If any uncomfortable symptoms occur during use, the drug should be discontinued immediately and a hospital visit should be made if necessary.