Ultrasonography, also known as acoustic contrast, is a technique that uses contrast agents to enhance the backscattered echoes and significantly improve the resolution, sensitivity and specificity of ultrasound diagnosis. With the improvement of instrument performance and the emergence of new acoustic contrast agents ultrasonography has been able to effectively enhance the two-dimensional ultrasound images and blood flow Doppler signals of myocardium, liver, kidney, brain, uterus and other substantial organs, reflecting and observing the blood perfusion of normal and diseased tissues. It has an important significance. Studies have shown that acoustic imaging is superior to conventional ultrasound and Spiral CT in the diagnosis of the number of liver tumors. especially in the detection of sub-centimeter lesions below 1 cm, acoustic imaging can be superior to or at least as sensitive as Spiral CT. Compared with CT and MRI, acoustic imaging possesses more superior features, such as good safety, no allergic reactions, real-time, and relatively low examination cost. It has been seen as the third revolution after 2D ultrasound, Doppler and color flow imaging.