Parkinson’s disease is a chronic disease, and in some people it can last for more than a decade, for which it has also plagued them for a long time. The daily pain of the disease has an increasing impact on life and the quality of life is declining year by year. Because of the brain pacemaker surgery, his years of Parkinson’s disease were cured and his quality of life was improved. Ma developed tremors in his left fingers 10 years ago without any obvious cause, and then gradually progressed to tremors in his left upper limb and went to a local hospital, where he was diagnosed with Parkinson’s disease. After 2 years, the symptoms further worsened and tremor in the left lower limb and right limb appeared. The symptoms improved significantly, and then worsened when he did not take the medication. Three years ago, Ma began to experience slow movement, limb stiffness, difficulty turning over and undressing, and six months ago, the dose of medication was adjusted and the symptoms improved, and then the symptoms further worsened. Ma recovered well after stereotactic deep brain electrode implantation in our hospital in November 2018. In order to seek further treatment, he came to our outpatient clinic today and was admitted as “Parkinson’s disease”. After the disease, Ma’s mind was clear and his speech was not clear. His facial expression was reduced, and his neck was slightly resistant. When he was not taking medication, he had slight difficulty in turning over and getting up, and he walked slowly and leaned forward slightly when walking. His muscle tone was increased, and he had significant left-sided inflexible limb movement and tremors in all four limbs. The initial diagnosis was Parkinson’s disease (Parkin). She was admitted to the hospital and actively improved the relevant tests. The diagnosis of Parkinson’s disease was made, and the machine had been switched on and commissioned after surgery with good results. After consulting with Dr. Wang, she was instructed that she could be discharged from the hospital and take oral medication regularly. From the beginning of the drug treatment to the final treatment of brain pacemaker surgery, Ma had a long period of ten years. After a decade of repetitive medication, the pacemaker surgery finally helped him to stop worrying. Parkinson’s disease is a chronic progressive disease, and when medication does not work, surgery is required. The best time to undergo pacemaker surgery is after the “honeymoon period”.