One of the symptoms of malaria infection is that Plasmodium can be found in blood, bone marrow or sputum smears. Blood marrow or sputum smear to find Plasmodium is a method to check the disease. In the epidemic period of such disease, Plasmodium is more acute, with high fever and chills, coma and convulsions. The sudden high fever, chills and coma in infants and children in the epidemic area have a lot of impact on the health of the body and should be examined and treated in a timely manner to prevent the occurrence of other internal diseases. Blood bone marrow or sputum smear to find malaria parasite examination items: 1, blood picture erythrocytes and hemoglobin decline after several episodes, falciparum malaria is particularly serious; total white blood cell count can be slightly increased at the beginning, after normal or slightly low, white blood cell classification mononuclear cells often increase, and see phagocytosis with malaria pigment particles. 2.Plasmodium examination Blood smear (thin or thick film) staining to detect Plasmodium. And can identify the species of malaria parasites. Bone marrow smear staining to detect Plasmodium, the positive rate is higher than blood smear. 3.Serological examination Anti-malarial antibodies usually appear 2-3 weeks after infection, peak at 4-8 weeks, and then gradually decline. Nowadays, indirect immunofluorescence, indirect hemagglutination and enzyme-linked immunosorbent assay have been applied, and the positive rate can reach 90%. It is generally used for epidemiological examination.