Radiofrequency ablation is mainly used for the treatment of cardiac arrhythmia in clinic, and its disadvantages and harms are mainly related to preoperative anesthesia, intraoperative injury, and postoperative complications. 1. Preoperative anesthesia: radiofrequency ablation mainly adopts local anesthesia as anesthesia, and the anesthetics have certain respiratory inhibitory effect, and also have certain adverse effects on cardiac function. 2. Intraoperative injury: radiofrequency ablation has the risk of bleeding due to damage to blood vessels; the electrode may damage the surrounding myocardial tissues, such as the Hirschsprung’s bundle, which has different effects on myocardial electrical conduction according to the different parts of the injury. 3. Postoperative complications: atrioventricular block; cardiac perforation causing cardiac tamponade, etc., but the incidence is low. If there is any discomfort, it is recommended to consult a doctor in time and treat according to the doctor’s advice.