Due to the different physique and condition of individuals, there is no quick cure for bile reflux morning sickness, which is often treated by adjusting lifestyle and diet, taking medicines such as omeprazole, domperidone, bismuth potassium citrate, and surgery. 1. Adjusting lifestyle and diet: patients should avoid eating cold, spicy and other stimulating or greasy foods that are difficult to digest, avoid overeating, reduce the consumption of strong tea and coffee, and quit smoking and drinking to avoid increasing the burden on the stomach and intestines. Patients should also pay attention to avoid lying in bed immediately after eating, and raise the head of the bed when sleeping at night to reduce the occurrence of reflux. Usually pay attention to the appropriate strengthening of sports, to ensure adequate sleep, avoid staying up late, overwork, etc., to maintain a happy mood. 2. Take drugs: patients with increased gastric acid secretion or insufficient gastric power, etc., can take omeprazole, ranitidine and other drugs to reduce gastric acid gastric acid secretion; take domperidone, mosapride and other pro-dynamic drugs, to promote the emptying of gastric contents, in order to reduce the reflux, to reduce the feeling of bitterness in the mouth. Patients can also take bismuth potassium citrate and other mucosal protection drugs to protect the gastric mucosa. 3. Surgery: If the patient’s symptoms are severe, he/she may also consider undergoing surgery, such as gastro-duodenal anastomosis, to relieve reflux and reduce bitter mouth. Patients with bile reflux and morning sickness are advised to consult a doctor in time and accept treatment actively. The medication should be taken strictly according to the doctor’s instructions, and should not be used by oneself, so as to avoid delaying or even aggravating the condition.