There is no latest treatment for plasma cell leukemia, and the conventional clinical treatment is still with drugs, chemotherapy, hematopoietic stem cell transplantation and other treatments. 1. Drug therapy: Usually, various drugs can be applied under doctor’s guidance, such as vincristine, cyclophosphamide, prednisone, erythromycin, desmethoxymethyl erythromycin and so on, and some plasma cell leukemia patients can choose etoposide, cisplatin, cytarabine and so on. 2. Chemotherapy: chemotherapy program is generally chosen is VAD program, that is, the use of adriamycin, dexamethasone, thalidomide and other treatment of multiple myeloma program to control the condition. For patients with bone destruction, zoledronic acid can be used for treatment, and some patients may even have bone repair. 3. Hematopoietic stem cell transplantation: i.e. the transplantation of allogeneic hematopoietic stem cells. When the transplantation is carried out, attention should be paid to the problems of whether there is any secondary serious infection and the susceptibility to graft immunity host after bone marrow transplantation. Apply high doses of drugs such as Marfan. Radiation therapy can be performed when available. Patients with plasma cell leukemia should go to the hospital in time if they have symptoms such as dizziness, fatigue, pallor, etc., and carry out standardized treatment under the guidance of doctors. Daily life should be light, do not eat spicy and stimulating food.