The common reasons for the friction and pain on both sides of the anus are perianal skin breakage, hemorrhoids, perianal inflammation and so on. 1. Perianal skin breakage: because the clothes are too tight, walking for a long time or sweating too much and other reasons lead to clothing continue to friction with the perianal skin, resulting in perianal skin breakage. The broken skin continues to be rubbed by clothing or stimulated by sweat, which will produce a hot and painful feeling. 2. Hemorrhoids: Hemorrhoids are often caused by poor circulation in the venous plexus of the anal canal or lower rectum, resulting in localized enlargement. Especially external hemorrhoids, when the meat on both sides of the anus friction, there will be obvious perianal pain, such as spicy pain. 3. Perianal inflammation: Perianal inflammation refers to the inflammation that occurs when feces or other inflammatory secretions irritate the perianal skin. Under the action of feces or other inflammatory secretions and other substances, the perianal skin will appear red, swollen, painful, itchy, oozing and other clinical manifestations. If the flesh on both sides of the anus friction spicy pain, to pay attention to, timely to the hospital to identify the cause of the disease, follow the doctor’s instructions by a professional doctor to implement individualized treatment.