Due to long-term friction, compression, caused by plantar skin hyperplasia, hypertrophy, accompanied by roughness, clinically most commonly seen in callus, the specific treatment is as follows: 1, skin care: patients pay attention to moisturizing, skin care, you can apply hand cream. 2, topical drugs: patients appear mild hyperplasia, hypertrophy, you can mix salicylic acid ointment and urea vitamin E cream for external use. 3, liquid nitrogen freezing treatment: patients appear plantar skin thickening obvious, accompanied by tactile disorders, you can go to the dermatology department for liquid nitrogen freezing treatment. After the above treatment, the symptoms can be quickly relieved and cured. 4.Botulinum toxin closure treatment: Patients in the treatment process, if the plantar skin is increasingly thickened, and accompanied by pain, affecting walking, can be under the guidance of dermatologists, oral vitamin capsules, but also local Botulinum toxin closure treatment can be performed. During the treatment period, it is necessary to wear soft-soled shoes, pay attention to rest and reduce walking.