Infantile colic is generally referred to the pain and discomfort caused by intestinal spasm, which is mostly manifested by repeated crying, stretching of arms and legs, and so on. Usually infants in the case of intestinal spasm, most of the sudden paroxysmal abdominal pain, usually each attack lasts 3 to 5 minutes, and each interval time for several minutes to tens of minutes, and most of them can be relieved in dozens of minutes to several hours, individual patients can also be repeated attacks for several days. The degree of abdominal pain varies, and most patients with mild symptoms can tolerate it, which may be characterized by irregular, paroxysmal and repeated crying. If the symptom is severe, it may appear hand and foot stretching, rolling, sweating, pallor, refusing to press the abdomen and other symptoms. At the same time, the site of pain will also vary with the part of the spasm, if the spasm occurs in the small intestine, most of the pain around the umbilicus, if the spasm occurs in the distal colon, most of the left lower abdominal pain. If the spasm occurs in the proximal colon and ileum, right lower abdominal pain may occur. For patients whose spasms occur in the descending and sigmoid colon, the pain may be accompanied by the urge to have a bowel movement or may occur before defecation. If the spasm occurs in the hepatic or splenic region of the colon, the pain is mostly located in the quaternary region. In addition to this, infants with colic may experience a loss of appetite, poor mental performance, and difficulty sleeping. Since infants are unable to pinpoint the exact location of their discomfort, the clinical manifestation may be mainly crying caused by the discomfort, which lacks the specificity of the disease. Parents should pay more attention to the status of their infants, and seek prompt medical attention if any of the above abnormalities occur, so as to avoid delaying the treatment.