Medications for bone pain include non-steroidal anti-inflammatory drugs (NSAIDs) and some topical pain relievers. 1. Non-steroidal anti-inflammatory drugs: the first-line drugs include celecoxib, diclofenac sodium, meloxicam, and loxoprofen sodium, etc. These drugs can play a good role in eliminating sterile inflammation and temporarily relieve pain. It is important to note that patients with gastrointestinal diseases such as gastric ulcer, chronic gastritis, etc. are recommended to use selective COX-2 inhibitors of anti-inflammatory drugs, such as celecoxib, because selective COX-1 inhibitors will aggravate gastrointestinal tract irritation. 2. Topical painkillers: If the above drugs do not work well or because of other diseases can not take drugs can be used to use topical painkillers, such as the use of diclofenac diethylamide ointment for local application. The use of medication should be carried out under the guidance of a doctor, not unauthorized use of medication.