Which is the best anesthetic drug, this question is very broad, because there are many kinds of anesthetic drugs, local anesthesia, inhalation anesthesia, intravenous anesthesia about these three kinds, there are other narcotic analgesics for cancer pain, postoperative analgesia. Anesthetic drugs which is good, with the development of science and technology now, many drugs have very little side effects, such as local anesthetics most of the application of lidocaine, ropivacaine; general anesthetics generally inhalation anesthesia, the choice of sevoflurane is better, sevoflurane this kind of inhalation anesthesia, postoperative agitation of the patient is relatively small, and now clinically a lot of tertiary hospitals use sevoflurane inhalation anesthetics. Intravenous anesthetics have isoproterenol, ketamine, etomidate, the most commonly used isoproterenol can be awakened in 5-10 minutes after stopping the drug, and there is no other discomfort after awakening. Ketamine, an intravenous anesthetic, is mostly used for pediatric surgery. Narcotic analgesics, morphine, pethidine, fentanyl, etc., most of the side effects of nausea, vomiting, skin itching, these analgesics can generally be metabolized 48 hours after surgery. Therefore, the choice of which anesthetic drug is best may also be based on the site of surgery.