The term “hepatic occupying lesion” is a medical imaging diagnostic description that is usually found in the findings of ultrasound, CT, MRI, etc. It refers to an abnormal echogenic area or density area in the liver parenchyma on top of the homogeneous echogenicity of normal liver ultrasound or homogeneous density of CT or MRI, etc. It generally refers to an abnormal mass of tissue in the liver parenchyma without reference to the cause and nature of the mass, and is not synonymous with liver cancer. Hepatic occupying lesions can be classified into benign and malignant lesions depending on their nature. Malignant hepatic occupying lesions mainly include primary hepatocellular carcinoma, metastatic hepatocellular carcinoma, hepatic sarcoma, hepatocystic adenocarcinoma, hepatoblastoma, lymphosarcoma, etc., among which primary hepatocellular carcinoma is the most common. Benign hepatic occupying lesions mainly include hepatic hemangioma, hepatocellular adenoma, inflammatory pseudotumor, focal nodular hyperplasia, limited fatty infiltration, hepatic cyst, hepatic abscess, liver encapsulation disease, smooth muscle tumor, teratoma, and malignant tumor, among which hepatic hemangioma and hepatic cyst are common. If a liver-occupying lesion is detected on examination, it should be seen early in the hospital so that the doctor can confirm the cause and nature of the lesion. For the diagnosis of liver-occupying lesions, various imaging methods (liver-enhanced CT, MRI, PET-CT, ultrasonography, hepatic arteriography, etc.) are available to confirm the location, size, number, and nature of liver-occupying lesions, and combined with the patient’s relevant medical history, clinical signs, laboratory blood tests, etc., the cause and its benign and malignant nature can be accurately diagnosed. Based on the location, size, number and nature of the liver-occupying lesion and the patient’s physical condition, the doctor will develop individualized conservative or surgical treatment strategies to remove the patient’s disease and restore the patient’s health as soon as possible. Therefore, once a liver-occupying lesion is detected, you should go to the hospital and consult a specialist to avoid delaying the condition and treatment.