Dexamethasone acetate efficacy and treatment

Dexamethasone acetate is a glucocorticoid with anti-inflammatory, anti-allergic and immunosuppressive effects. In clinical practice, it is mainly used for allergic and autoimmune inflammatory diseases. Such as connective tissue disease, severe bronchial asthma, etc., but also for the diagnosis of certain adrenocortical diseases such as dexamethasone suppression test. Dexamethasone acetate is a long-acting glucocorticoid, an adrenocorticotropic hormone and a fluorinated derivative of prednisolone. Its anti-inflammatory, anti-allergic, and anti-shock effects are superior to those of prednisone, while it has little effect on sodium accumulation and promotion of potassium excretion, and has a strong pituitary-adrenal inhibitory effect. In clinical practice, it is mainly used in allergic and autoimmune inflammatory diseases. For example, connective tissue disease, severe bronchial asthma, dermatitis and other allergic diseases, ulcerative colitis, acute leukemia, malignant lymphoma. In addition, the drug is used in the diagnosis of certain adrenocortical diseases – dexamethasone suppression test. Adverse reactions such as diabetes, infections, peptic ulcers, Cushing-like syndrome may occur after the use of the drug. It is contraindicated in case of allergic sensitization to the product. It is contraindicated in patients with hypertension, thrombosis, glaucoma. Note that it is used with caution in patients with tuberculosis, acute bacterial or viral infections, and when application is necessary, appropriate anti-infective treatment must be given. After long-term use, the dosage should be gradually reduced before stopping the drug. Dexamethasone acetate is recommended to be used under the guidance of a doctor, and should not be used on its own to avoid adverse effects.