Painful urination, i.e. painful urination, can be seen in acute cystitis, urinary stones, etc. There is no fastest treatment, the treatment is mainly medication and surgical treatment. 1. Cystitis: rest, drink more water, urinate regularly, choose antibiotic furotoxin, fosfomycin, amoxicillin and so on. 2. Urinary stones: less than 0.6cm stones can choose drug treatment, such as uric acid stones can choose sodium citrate; less than or equal to 2cm kidney stones, ureteral stones, the choice of extracorporeal shock wave treatment, or the use of transurethral ureteroscopy lithotripsy surgical treatment and so on. When urinary pain occurs when urinating, you should go to a regular hospital in a timely manner, under the guidance of a professional doctor to choose the appropriate treatment, the above drugs need to be used in accordance with the doctor’s instructions.