The skull is a very important group of bone tissue in the human body, which plays an important role in protecting and supporting the brain, the soft tissues in the skull and the organs of the head and face. It can be seen that the skull plays a very important role in the life operation of the whole body and the health of the human body. However, cranial defect is a common craniofacial disorder, so cranial bone repair should be performed in time. Cranial defects can cause great damage to the human body and seriously endanger life and health. First of all, the lack of skull bone will have a greater impact on the skull shape, which is very unattractive; in addition, the lack of hard skull bone protection, the brain is easily damaged by the outside world, which is very unsafe; there is also a large range of skull defect, the patient’s local scalp sinking due to atmospheric pressure, which may lead to intracranial pressure imbalance, brain tissue displacement and cerebral hemisphere blood flow reduction and cerebrospinal fluid circulation disorder, thus causing a series of clinical manifestations, mainly including: headache, vertigo, irritability, epilepsy, discomfort with no other explanation, and various mental disorders. After craniosynostosis, patients are also prone to have some low self-esteem, autism and other negative emotions, which are a serious blow to patients psychologically and mentally. It is thus clear that skull repair surgery should be performed promptly after skull defect occurs. The cost of skull repair surgery is affected by many factors. The cost of cranial repair includes the cost of surgery, hospitalization, materials, anesthesia, nursing care, post-operative medication and so on. Generally, hospitals will charge according to the national standards and regulations, which are fair and standardized. The cost of materials is the most influential. For example, the titanium mesh material commonly used in clinical practice may be relatively low in cost, but there may still be some problems in use, such as post-operative rejection, infection, abrasion of the scalp, material exposure, post-operative heat and cold sensitivity, affecting CT MRI and so on. There is a new polymer material, polyether ether ketone PEEK material, although the cost may be slightly higher, but the performance is very good, very good to overcome the above problems of titanium mesh material, highly favored by neurosurgeons and patients with cranial defects, and become a new trend of cranial repair materials.