Shingles is a common and frequent disease that occurs more frequently in the elderly. Because of the decreased immune function in the elderly, the virus is more likely to be activated, revived, multiplied, and then transmitted down the nerves to the skin to form herpes zoster. At the same time, it invades and destroys the nerves, causing nerve damage, so it is easy to leave the manifestation of neuralgia. For herpes zoster neuralgia in the elderly, our most important treatment has three parts: 1. early and early antiviral treatment to effectively inhibit virus recovery and reproduction, control the virulence of the virus and damage to the nerves, and reduce the damage to the nerves as early as possible; 2. at the same time, regulate the immune function of elderly patients, effectively improve the immunity of patients, which can also have a certain inhibitory effect on the virus; 3. neuroprotective or neurotrophic drug treatment, to protect the nerve before nerve damage, anti-inflammatory reaction of the nerve, and then use nutritional drugs to protect the nerve myelin sheath, to avoid further damage to the nerve, is also an effective control of neuralgia. After the formation of nerve damage and necrosis, we put more emphasis on active and effective neurotrophic drug therapy to promote nerve repair, so as to achieve the complete treatment of pain.