High VEGF 316 does not need to be treated in women during pregnancy or trauma healing, but if it is caused by other diseases, it is important to go to the appropriate department in time. Vascular endothelial growth factor is a functional glycoprotein with high biological activity. The normal reference range is 41.5-91.1 pg/ml. a VEGF value of 316 pg/ml suggests that the factor is higher than normal. The causes of elevated VEGF are physiologic and pathologic. 1. Physiologic elevations are mainly seen in women during pregnancy and trauma healing and do not require treatment. 2. Pathological elevation is mainly seen in certain diseases, such as acute myocardial infarction, atherosclerosis, nephropathy, diabetic nephropathy, tumors, vasculitis and so on. It is necessary to go to the corresponding departments, such as cardiology, nephrology, oncology and rheumatology. Therefore, when the test value is pathologically abnormal, you should go to the hospital and be treated by the doctor after combining other clinical symptoms and signs to determine the cause.